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China Pharmacy ; (12): 1911-1915, 2022.
Article in Chinese | WPRIM | ID: wpr-936502

ABSTRACT

Euryale f erox is the dry and mature seed kernel of Euryale ferox Salisb.,the effect of raw E. ferox is mainly to astringe spontaneous emission or leukorrhea ,while the effect of fried E. ferox is mainly to tonify the spleen and stomach. Therefore , processing has an important impact on the effect of E. ferox . The author summarizes the processing evolution ,chemical composition , pharmacological action and quality control of E. ferox by consulting past materia medica monographs and related research papers. The results show that the processing methods of E. ferox in the past include cleansing ,medicinal juice ,frying and steaming ;modern processing methods mainly continue to use cleansing and frying ,among which frying can be divided into stir-frying and bran-frying. E. ferox mainly contains polyphenols ,flavonoids,sterols and other components ,with antioxidant ,antibacterial,hypoglycemic and other pharmacological effects. At present ,scholars have established a variety of fingerprints to control the quality of E. ferox . Naringin,total amino acids and other components may be the differential components that affect the quality of E. ferox ,while the contents of heavy metals and sulfur dioxide are important indicators that affect the safety of E. ferox ,and α-tocopherol and gallic acid may be the quality markers of E. ferox . Later ,according to the basic properties of raw and processed products of E. ferox , pharmaceutical analysis methods can be used to comprehensively investigate the differences and change rules of chemical components in E. ferox before and after processing. The pharmacodynamic effects of E. ferox before and after processing can be evaluated by in vivo and in vitro models,so as to provide references for the inheritance of processing technology ,the formulation of processing standards and clinical application of E. ferox .

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